Bees make propolis, which they use to glue the materials of their hives together, by mixing beeswax and other secretions with resins from the buds of conifers. Those resins have natural germicidal properties.
Propolis does have proven antibiotic and antiseptic properties, and may also have antiviral and anti-inflammatory effects. I consider it safe and useful as a home remedy. You can find it in various forms in health food stores or get the raw stuff from beekeepers. I recommend it as a good topical treatment for uncomplicated wounds and, when used as a gargle or in spray form, as a remedy for sores and irritations in the mouth. I use propolis in tincture form to treat canker sores and sore throats.
If you have had an allergic or hypersensitivity reaction to bee stings or bee products including honey, you could react to propolis in the same way.